NEUROPSYCHOLOGY

Psychology 222

Autumn 1996

Meeting Times:
Class: MWF: 9:00-9:50Laboratory: R: 8 - 11 AM or 1 - 4 PM
Instructor: John H. Krantz
Office: Science Hall 112Office Hours: TBD by class
Phone: x7307E-mail Address: krantzj@hanover.edu

Text:

Our principle text will be Physiology of Behavior, 5th ed. by Neil R. Carlson. There is a report from the Hastings Center on reserve at the library that will serve as a background for our discussion/debate on the handling, care and use of animals in the laboratory. Other readings will be handed out as necessary.

Objectives:


The central nervous system, composed of the brain and spinal chord, is the control center of the body; however, it is a jelly-like mass encased in fluid-filled sacks again encased in bone. How do these buried structures carry on the tasks of learning about the environment around us, controlling our movements so precisely, helping us survive individually and as a species, causing us to experience finely-tuned emotional reactions, learning, remembering, speaking so well? That is the goal of this class: To bring some light to this greatest of all human mysteries. Our answers are at best tentative, but we have learned much and the hints at the final answers are, I find, exciting. In this course I will use the most common way of thinking about the brain: as a very sophisticated computer. This represents the information processing approach and is the mainstay of neuropsychology today. Don't get too caught up in the computer analogy. While we understand that the brain does not operate in the same way as the PC or Macintosh on your desk, it is helpful to use some of the terminology from computer functions to understand brain functions, e.g., input for bringing in information about the outside world.

The goals of the laboratory portions of the class are: (1) to gain first-hand knowledge of neuroanatomy, (2) to gain experience in the handling, care, and proper use of laboratory animals, and (3) to acquaint you with some of the behavioral methods used to study brain-behavior relations.


Course Outline:

Material covered in any course that you take here at Hanover College represents more than a collection of facts or ideas loosely held together by the course title. There is an intricate structure to what is included and what is not which makes that course content distinct from other courses. I find, however, that in the heat of a term, students and faculty get caught up in the particulars of the day's lecture and sometimes lose sight of how the specifics of the day's lecture fit into the overall structure of the course. It is a "lose sight of the forest for the trees" type of phenomenon. In order to help you understand and keep track of the overall structure of this course, I have prepared the following course outline. The reading assignments below have the outline numbers next to them so that you can refer back to this outline and understand how a particular topic relates to the whole area of learning. In addition, during the class periods I will refer each lecture back to this outline. Study this outline. It will be of great help in studying for the examinations and especially the comprehensive portion of the final examination where I will ask you questions that will cross several portions of this course.

NOTE: Two abbreviations are used under the reading heading below. There meanings are:

ChChapter in the text. If only part of the chapter is required, page numbers will follow.
CDAn article out of Current Directions in Psychological Science. A short reference follows with V refering to the volume the article is in and the page numbers follow the volume number. The complete reference is given at the end of the course outline.

Date

Days

Topic

Reading
Sep 2-4M,W I. Overview: Philosophical Issues of Neuropsychology Ch 1
II. Structure and Function of the Nervous System
A. Small Scale Structures
Sep 6F 1. StructureCh 2: 20-29
Sep 9M 2. Transmission within a Neuron Ch 2: 30-44
Sep 11W 3. Communication between Neurons Ch 3: 47-70
Sep 13-16F,M 4. PsychopharmacologyCh 3: 70-74
Sep 18-20W,F B. Large Scale Structures of the Central Nervous System Ch 4
Sep 23M C. Physiological Methods in Neuropsychology Ch 5
Sep 25WTest #1

Before this test you are required to complete the neuron and brain structure tutorials and quizzes found at

http://psych.hanover.edu/Krantz/neurtut220.html

Failure to do these tutorials will affect your final grade (maximum - 1/2 letter grade). Constructive Comments will be given extra credit.

III. The Input and Output of the Nervous System
A. Input (Sensory Systems)
Sep 27F 1. General Issues of Sensory Coding
Sep 30-Oct 4M,W,F 2. VisionCh 6
As part of your reading assignment please check the Receptive Fields Tutorial at:

http://psych.hanover.edu/Krantz/sen_tut.html

Oct 7M 3. AuditionCh 7: 182-197
Oct 9W 4. Mechanical and Chemical Senses Ch 7: 198-223
Oct 11-16F,W B. Output (Motor Systems) Ch 8
Oct 18FTest #2, Wednesday February 21
IV. Basic Motivated Behaviors
A. Behaviors Necessary for Individual Survival
Oct 21M 1. General Model and ThirstCh 12
Oct 23W 2. HungerCh 13; CD V3, 9-151
Oct 25-28F,M 3. SleepCh 9; CD V2, 34-392
B. Behaviors Necessary for Species Survival
Oct 30W 1. Sexual BehaviorCh 10:291-322
Nov 4M 2. Maternal BehaviorCh 10:324-330
V. Higher Functions
Nov 6W A. Emotional Reactions (Not typically called a higher function, but seems to fit for our purposes.) Ch 11
Nov 8FTest #3 Wednesday March 20
B. Rational/Cognitive Functions
Nov 11-13M,W 1. Learning and MemoryCh 14, Ch 15
Nov 15-18F,M 2. Cerebral AsymmetryCh 16: 512-540; CD V2,21-253
VI. Variations and Development of the Brain
A. Development and Variations in Development
Nov 20W 1. General Principles of Brain Development
Nov 22F 2. Visual Development/Abnormalities
B. Brain Trauma and Dysfunction
Nov 25-Dec 2M,M 1. Neural Basis of Mental Disorders Ch 17,Ch.18
Dec 4-6W,F 2. Brain Damage and its Recovery CD V1 164-1694; CD V2, 56-655
Readings from the last section of the course will come from The Whole Brain Atlas which is an online resource. The sections will be assigned later. You will find The Whole Brain Atlas from a link on

http://psych.hanover.edu/Krantz/neurtut220.html

Dec 9-13Final Exam

References for Current Directions In Psychological Science (CD) Articles:

  1. Stanley, B. G. & Gillard, E. R. (1994). Hypothalamic neuropeptide Y and the regulation of eating behavior and body weight. Current Directions in Psychological Science, 3, 9-15.
  2. Foster, R. G. (1993). Photoreceptors and circadian systems. Current Directions in Psychological Science, 2 34-39.
  3. Hellige, J. B. (1993). Unity of thought and action: Varieties of interaction between the left and right cerebral hemispheres. Current Directions in Psychological Science, 2, 21-25.
  4. Farah, M. J. (1992). Is and object and object and object? Cognitive and Neuropsychological investigations of domain specificity in visual object recognition. Current Directions in Psychological Science, 1, 164-169.
  5. Ramachandran, V. S. (1993). Filling in gaps in perception: Part II. Scotomas and phantom limbs. Current Directions in Psychological Science, 2, 56-65.

LABORATORY SCHEDULE AND READING ASSIGNMENTS.

WeekOutline Topic/Assignment
II.B:Sheep Brain Dissection I
III.B:Sheep Brain Dissection II It might help to review the brain tutorials at:

http://psych.hanover.edu/Krantz/neurtut220.html

IIII.B:Sheep Brain Practicum/Handling and Care of Laboratory Animals - Hastings 4-19
IVIV.B:Learning and Shaping I
VIV.B:" " " " II
VIIV.B:" " " " III
VIIIV.B:" " " " IV
VIIII/0:Circadian Rhythm I/Laboratory Report 1 due
IXI/0:" " " " II
XI/0:" " " " III
XIIV.B:Cerebral Asymmetry I/Laboratory Report 2 due
XIIIV.B:" " " " II
XIIILaboratory Report 3 Due


Examinations:

There will be four examinations. In a course of this type, all later information builds upon the foundation developed in earlier parts of the course. Therefore the course is cumulative and so are the examinations. Each examination will cover material from all previous sections of the course. Since later examinations will be covering more material they will be worth more points. The value of the examinations are as follows:

Exam 150 points
Exam 2100 points
Exam 3150 points
Exam 4200 points

The first three examinations will be one hour in length and the final will be twice as long since it is the course ending examination.

Laboratory Reports:

Lab reports are required for the three experiments that will be conducted as part of the lab course. Each report is due one week after the lab is completed at the beginning of the lab period. For each day that the lab report is late, you will lose one letter grade. More information regarding how these reports are to be prepared will be given to you on the lab day on which we discuss the lab reports.

Laboratory Grading:

For the first laboratory, the sheep brain dissection, there will be a practicum worth 150 points. The first laboratory report will be worth 50 points and only covers part of the full laboratory report. The second laboratory report will be worth 100 points and the final laboratory report will be worth 150 points. Thus the laboratory portion of the course will be worth 450 points.

Network Use Assignments:

Hanover College has established a computer network that is local to the campus and established links to the Internet which stretches around the world. The implications and possibilities of such computer communications strikes me as staggering and to a great extent unrealized. However, I find it important that you begin gaining experience with at least some aspects of the network because it will alter many aspects of at least your work lives, by providing access to information not previously available, and probably your home lives in the context of the information highway. Therefore, I have designed a few small assignments to give you experience on the network in ways that I believe will shape the future of Neuropsychology.

Assignment:

  1. Get this syllabus. It must be brought to class by Wed. Sep 4. (10 points)
  2. Create a file in a word processor of your choice. Save the document as a text file and include that file to me in another e-mail message (this is a second message). I will cover the specifics for this assignment in a laboratory class. Both assignment 1 and 2 must be completed one week before the first laboratory report is due as you will use these techniques to submit your laboratory reports. (20 points) Due end of second week.
  3. The first assignment allows you to communicate with friends and send papers around the world if they have e-mail. However, we have just scratched the surface of the network. There are many ways to get information off the network. The easiest way is to use the web browser called Netscape. In the computer labs you will be taken to the Hanover College Home page. From there click on the button that says Departmental Servers. There you will find a link to the Psychology Department. From here you will have a base to explore psychological information around the world. One way science may be changed by the Internet is by the use of electronic journals. On the psychology home page is a link to a page with a list of electronic journals. Explore these and find a complete article having to do with the brain and behavior and print it out and hand it in. (20 points). Due end of third week.

Class Participation and Miscellaneous Grades:

To help ensure that students actively participate there is a participation grade. In addition I reserve the right to give other small assignments and quizzes as I see fit to best benefit the quality of the class experience. The points for this section is 150 points. At least 100 will be participation. Up to the other 50 points could be short in class quizzes, or other network assignments or perhaps a reading assignment. These will be clearly announced with their point value. What ever is not used in these assignments will be part of the participation grade..

Grading:

There are a total of 1150 points in this class, the grades will be assigned as follows:

Grade
Points Needed
A
1150 - 1035
B
1034 - 920
C
919 - 805
D
804 - 690
F
< 690



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